Article | 21.06.2020
Influence of Water Disinfection on the Stability of Antibiotics in Drinking Water
Marketing authorization or registration dossiers are required to follow recommendations as described in the EMEA/CVMP/540/03-Rev1 guideline on assessing the stability of antibiotics to be administered in drinking water. However, there are currently no requirements or data available on the compatibility of disinfectants and antibiotics. This article describes the influence on the stability of 10 veterinary products in combination with 50 ppm hydrogen peroxide (H2O2) and sodium hypochlorite (0.5 ppm active chlorine) at two different concentrations (the normal concentration in drinking water, and the concentration when using a stock solution for a proportioner = 20 x normal concentration).
