TYLOVET® Soluble

(tylosin tartrate)

Soluble Powder for Chickens, Turkeys, Swine, and Honey Bees

COMPOSITION

Spores of Bacillus subtilis min 6.4 x 109 CFU*/g

Indications

Chickens

As an aid in the treatment of chronic respiratory disease (CRD) associated with Mycoplasma gallisepticum in broiler and replacement chickens; and for the control of CRD associated with Mycoplasma gallisepticum at the time of vaccination or other stress in chickens. For control of CRD associated with Mycoplasma synoviae in broiler chickens.

Turkeys

For maintaining weight gain and feed efficiency in the presence of infectious sinusitis associated with Mycoplasma gallisepticum.

Swine

For the treatment and control of swine dysentery associated with Brachyspira hyodysenteriae. Honey Bees

For the control of American Foulbrood (Paenibacillus larvae).

Dosage and Administration

Mixing (concentrated solution): To assure thorough dissolution, place the entire contents of one pouch of Tylovet in a mixing container and add one gallon of water (3790 mL) to the Tylovet Soluble Powder. Always add water to the powder. Do not pour the powder into the water. Prepare a fresh solution every three days.

Chickens

Mix the concentrated solution with water to make 50 gallons (189 liters) of treated drinking water. Treat for 3 days (1 to 5 days depending upon severity of infection). Treated chickens must consume enough medicated water to provide 50 mg per pound of body weight per day. Only medicated water should be available to the birds.

Turkeys

Mix the concentrated solution with water to make 50 gallons (189 liters) of treated drinking water. Treat for 3 days (2 to 5 days depending upon severity of infection). Treated turkeys must consume enough medicated water to provide 60 mg per pound of body weight per day. Only medicated water should be available to the birds.

Swine

Mix the concentrated solution with water to make 400 gallons of treated drinking water (250 mg/gal). Treat for 3 to 10 days, depending upon severity of infection. Treated swine must consume enough medicated drinking water to provide a therapeutic dose. Only medicated drinking water should be available.

Honey Bees

Colonies should receive three treatments administered as a dust in confectioners/powdered sugar. Mix 200 mg of tylosin in 20 g confectioners/powdered sugar (use immediately). Apply over the top of the brood chambers once weekly for 3 weeks.

Note: In all species, if improvement is not observed after recommended treatment, the diagnosis and susceptibility of organisms should be reconfirmed. Medicated water should be the only source of drinking water during the treatment period. Prepare a fresh tylosin solution every 3 days.

Warnings

Treated pigs must not be slaughtered for food within 48 hours after treatment. Treated chickens must not be slaughtered for food within 24 hours after treatment. Treated turkeys must not be slaughtered for food within 5 days after treatment. Do not use in layers producing eggs for human consumption. For honey bees, the drug should be fed early in the spring or fall and consumed by the bees before the main honey flow begins, to avoid contamination of production honey. Complete treatments at least 4 weeks prior to main honey flow. Note: Direct contact with skin or mucous membranes during mixing may cause irritation. Avoid inhalation. Keep out of reach of children.

Storage

Store at room temperature 25°C (77°F). Protect from humidity.