VITAMIN C

solution for injection

COMPOSITION

PHARMACOLOGICAL ACTION

Ascorbic acid participates in the oxido-reductive processes and aids the tissue respiration. It reduces the permeability of the membranes, thickens the capillaries and helps to restrict the exudative, inflammatory and partly the allergic reactions. It induces antitoxic and desensibilizing effect. Its antipermeability effect is increased by vitamin P – like substances (rutin, troxerutin and other bioflavonoids). Ascorbic acid facilitates the transformation of folic acid into folinic acid and stimulates erythropoiesis indirectly. It improves reticuloendothelium function. Ascorbic acid stabilizes adrenaline and assists the synthesis of corticosteroid hormones. It exhibits a hemostatic effect. It improves the appetite, the secretion activity of the digestive tract and the animal growth. It is rapidly consumed in febrile conditions. Applied in excessive doses it acts as an immunostimulant.

INDICATIONS

Vitamin C deficiency; inflammatory febrile diseases (contagious and non-contagious) - pneumonia, bronchopneumonia, rheumatism, hepatitis, nephritis, enterocolitis, furunculosis; in heart ascites, hemorrhages, hemorrhagic diathesis; in exudative states, allergic diseases - urticaria, pollinosis; in intoxication with toxins and medicaments (arsenic compounds, heavy metals, phenols, including salicilates, sulphonamides, barbiturates, synthetic estrogens, alcohol); hypochromic anemia; wounds and fractures of retarded recovery; dental damages; pregnancy, in cases of intensive lactation; increased function of the thyroid gland; hypofunction of the hypophysis and the suprarenal gland; for increase of the resistance to higher environment temperatures in poultry; as an immunostimulant (non-specific); in bacterial and viral diseases, etc.

MODE OF ADMINISTRATION

Intramuscularly, intravenously, subcutaneously, orally.

TARGET SPECIES

Large ruminants, calves, little horses, sheep, goats, pigs, lambs, piglets, dogs.

DOSAGE

Intramuscularly

SPECIES	Vitamin C solution for injection, ml
Large ruminants	10 – 20, in some cases 100 – 200
Calves and little horses	2 – 5
Sheep, goats and pigs	3 – 8 – 10
Lambs, kids and piglets	2 – 3
Dogs	0.5 – 1.0

Intravenously

SPECIES	Vitamin C solution for injection, ml
Large ruminants	5 – 10, in some cases 100 – 200
Horses	5 – 8, in some cases 100 – 200

Subcutaneously

SPECIES	Vitamin C solution for injection, ml
Large ruminants	10 – 20
Horses	20 – 40
Dogs	0.25 – 0.75

Orally - therapeutically (with respect to pure substance)

SPECIES	Vitamin C solution for injection, g
Large ruminants	0.7 – 3.5
Horses	0.5 – 2.5, in some cases up to 5.0
Small ruminants	0.2 – 0.8, in some cases 1.0
Pigs	0.1 – 0.4
Dogs	0.03 – 0.08, in some cases 0.5
Cats	0.01 – 0.03, in some cases 0.1
Hens	0.004 g/ kg b.w. in cases of heat stress
For heat stroke	0.02 g/ kg b.w. with the drinking water 0.05 – 0.15 g/ kg b.w. with the feed

WITHDRAWAL PERIOD

Zero (0) days.

STORAGE

In the original packing, well closed, in dry and well-ventilated facilities, protected from direct sunlight at temperature between 8° and 15°C.

SHELF LIFE

Two (2) years from the date of manufacture.

PACKAGING

Multidose vials of 50 ml.