VIALITON

solution for injection

COMPOSITION

Retinol (vitamin A)	50 000 IU
Cholecalciferol (vitamin D3)	25 000 IU
d,l-alfa-tocopherol acetate (vitamin E)	20 mg
Excipients	up to 1 ml

PHARMACOLOGICAL ACTION

It is determined by the action of the three vitamins on the metabolism of mammals and birds. Vitamin A (retinol) plays an important role in the process of biological oxidation – it regulates phospholipid and cholesterine metabolism, activates insulin action. It contributes to the normal build-up and development of skin and mucosal epithelial cells, enhancing the epithelial tissue resistance against physical, chemical and microbial injuries. It sustains turgor and transparency of corneal cells. Vitamin A insures regular fetal development, hinders the keratinization of the vaginal epithelium; encourages the growth of the young organism. After resorption, vitamin A is hydrolyzed in the liver. It is excreted with the urine in the form of metabolites. Vitamin D3 (cholecalciferol) helps the resorption of calcium and phosphorus compounds by the digestive tract; regulates their metabolism and ratio by ionizing them; facilitates their deposition in the bones and the formation of egg-shell in the birds. Vitamin D3 increases tissue metabolism, improves the functions of the digestive tract and of the liver. It has an antihistamine, cortisone-like and keratoplastic effect.

Vitamin E (tocopherol) is an antioxidant, which protects fats, vitamin A and steroid hormones in the organism from oxidative degradation, hence preventing the formation of toxic metabolites. It regulates the normal development and functioning of the gonadal epithelium as well as the fetal development. Supposedly, it plays a role in lipid metabolism and takes part in the synthesis of chromatin molecule in the cellular nuclei. It induces an effect on the function and the structure of smooth and striated muscles (the heart muscle included). It helps the resorption of iron compounds by the digestive tract and takes part in hemoglobin synthesis. It is excreted predominantly with urine in an unaltered and a metabolized form.

INDICATIONS

A, D3 and E hypo- and avitaminoses; for increasing the general resistance of the organism; muscular dystrophy in lambs, calves and foals; encephalomalacia in chickens; rachitis, osteomalacia and joint diseases; lesions of the skin and of mucosa; spermatogenetic disturbance and impotence of brood animals; for stimulation of egg-production and for increase of egg hatchability; in cases of growth retardation in pigs, calves, chickens, dogs and cats.

MODE OF ADMINISTRATION (Rp)

Intramuscularly, subcutaneously or orally.

TARGET SPECIES

Large ruminants, horses, calves, foal, piglets, pigs, dogs, cats, chickens.

DOSAGE

Intramuscularly, subcutaneously

SPECIES	Vialiton injection for solution, ml
Large ruminants and horses	10 – 20
Calves and foal	5 – 10
Pigs	4 – 8
Piglets	2 – 4
Dogs and cats	2 – 4

Orally, administered at the beginning of the day.

SPECIES	Vialiton injection for solution, ml
Chickens (100 animals)	10 – 20/ 2-3 l water

STORAGE

In the original packing, well closed, in dry and well-ventilated facilities, protected from direct sunlight at temperature between 8° and 15°C.

WITHDRAWAL PERIOD

Zero (0) days.

SHELF LIFE

One (1) year from the date of manufacture.

PACKAGING

Multidose vials of 100 ml.