TILMOVET®/BIOMICOSIN 30%

solution for injection

(tilmicosin)

COMPOSITION

	Tilmovet 30% solution for injection
Tilmicosin phosphate, equivalent to tilmicosin	300 mg
Excipients	up to 1 ml

PHARMACOLOGICAL ACTION

Tilmicosin, (20-deoxo-20-(3,5-dimethylpiperidin-1-yl)-desmycosin) is a chemically modified, long-acting macrolide antibiotic, applied in the veterinary medicine. It is active mainly against Gram-positive microorganisms and some Gram-negative microorganisms (streptococci, staphylococci, Pasteurella spp., mycoplasmas, etc.), as well as against mycoplasmas, etc. Tilmicosin reaches maximum blood levels in an hour after a single subcutaneous injection of 10 mg/ kg m. (=1 ml/ 30 kg m. of Tilmovet 30% solution for injection) and maintains high therapeutic concentrations in the target tissues for three days. It is concentrated in the lungs, penetrating intracellularly in the alveolar macrophages. It is eliminated mainly through feces and urine. Tilmicosin induces no teratogenic and embryotoxic effect.

INDICATIONS

For first-line control and treatment of Bovine Respiratory Disease (BRD). Also used for the treatment of respiratory bacterial diseases in large ruminants, caused by Pasteurella miltocida, Mannheimia (Pasteurella) haemolytica, infection processes associated with Haemophilus somnus, Histophilus spp. etc.

CONTRAINDICATIONS

Not established.

MODE OF ADMINISTRATION

Strictly subcutaneously, in the left 1/3 part of the animal neck (far away from the blood vessels).

Do not inject more than 15 ml at one injection site.

TARGET SPECIES

Cattle, sheep.

DOSAGE

Administer a single subcutaneous dose of 1 ml per 30 kg b. w.

SIDE EFFECTS

On rare occasions, a slight edema could occur which disappears quickly after some time.

WITHDRAWAL PERIOD

For meat – 28 days after the last administration.

STORAGE

In the original packing, well closed, in dry and well-ventilated facilities, protected from direct sunlight at temperature between 15° and 25°C.

SHELF LIFE

Two (2) years from the date of manufacture.

Three to six months after first opening of the containe

r.

PACKAGING

Multi dose vials of 50 ml and 100 ml.

WARNING

People handling the product must wear personal protective devices such as protective gloves of impermeable rubber and safety goggles and/or face shield.

Do not eat or smoke in the area of material storage. Wash the hands with soap before eating or smoking.