RODOTIUM® / VETMULIN® 45%

water-soluble granules

(tiamulin)

COMPOSITION

	Vetmulin / Rodotium 45% water-soluble granules
Tiamulin	45 g
Excipients	up to 100 g

PHARMACOLOGICAL ACTION

Tiamulin is a semi-synthetic antibiotic of the diterpene group active against Gram-positive (staphylococci, streptococci, clostridia, Corynebacterium, Erysipelothrix, Listeria) and Gram-negative (Pasteurella, Klebsiella, Haemophilus, Fusobacterium, Campylobacter, Bacteroides) microorganisms. Of particular significance is its activity against mycoplasmas (Mycoplasma hyopneumoniae, M. hyorhinis, M. hyosynoviae, M. gallisepticum, M. meleagridis) and spirochetes (Serpulina hyodysenteriae, S. innocens, S. pilosicoli, S. suis), etc.

INDICATIONS

For prevention and treatment of dysentery, colonic spirochetosis, spirochetal enterocolitis, enzootic bronchopneumonia and mycoplasmal arthritis in pigs; for prevention and treatment of chronic respiratory disease in chickens and turkeys.

CONTRAINDICATIONS

Tiamulin is incompatible with ionophore antibiotics hence animals must not receive products containing monensin, salinomycin, maduramicin or narasin during or for at least seven days before or after treatment with Rodotium 45% water-soluble granules.

MODE OF ADMINISTRATION (Rp)

Orally, with the drinking water.

Dissolve the prescribed quantity of the product in a small portion of water (for instance 50 g in 2:l), and further dilute the obtained concentrate with drinking water until the desired concentration has been reached. Daily prepare a fresh solution.

TARGET SPECIES

Pigs, chickens, turkeys.

DOSAGE

Pigs

For prevention and treatment of dysentery and other spirochetal enterocolitis:
- 100 g/ 1000 l drinking water (45 ppm with respect to tiamulin hydrogen fumarate) for 3-5 days. In severer infections the treatment may be repeated at a dose of 100 g/ 750 l water (60 ppm).

For individual treatment:
- 1 g of the preparation per 50 kg b.w. dissolved in 1 l of drinking water. For treatment of enzootic bronchopneumonia and mycoplasmal arthritis:
- 100 g/ 750 l water (60 ppm) for 3-5 days.

Chickens and turkeys

For prevention of chronic respiratory disease (CRD): - 100 g/ 360 l water (125 ppm) for 3-5 days;

For treatment of CRD:
- 100 g/ 180 l water (250 ppm) for 3-5 days. During the treatment only medicated water must begiven.

For prevention of CRD in newly-hatched chickens and turkey-poults:
- 100 g/ 360 l water in compliance with the following scheme:
- Days 1 to 3 after hatching 10 g of the product per 1000 chickens per day.
- Days 28-32 after hatching 65 g of the product per 1000 chickens per day.

SIDE EFFECTS

On rare occasions, erythema may occur in pigs which passes away without therapeutic treatment.

WITHDRAWAL PERIOD

For meat:

Pigs - 1 day after the last administration of the preparation.

Chickens - 7 days after the last administration of the preparation.

STORAGE

In the original container, well closed, in dry and well ventilated facilities, protected from direct sunlight at temperature between 15° and 25°C.

SHELF LIFE

Two (2) years from the date of manufacture.

PACKAGING

Sachets of 15, 100 and 1000 g. Fiber drums of 5, 10 and 25 kg.