ALLERGOVET 10% solution for injection

(diphenhydramine hydrochloride)

COMPOSITION

	Allergovet 10% solution for injection
Diphenhydramine hydrochloride	0.1 g
Excipients	up to 1 ml

PHARMACOLOGICAL ACTION

Diphenhydramine hydrochloride manifests an antihistaminic effect by blocking the H-histamine 1 receptors. It removes the effects observed as a result of the increased histamine content in blood and tissues, thereby affecting blood vessels and smooth muscles. It induces almost no effect on the secretory function of the gastric glands. It reveals also a sedative, local anaesthetic, ganglioplegic, anti-inflammatory and antitussive action.

INDICATIONS

For treatment of allergies, anaphylactic and inflammatory diseases - urticaria, allergic dermatides and dermatoses, allergic conjunctivitis, drug and feed related allergies, anaphylactic shock; aseptic total (diffuse) pododermatitis (laminitis acuta), periodic ophthalmia and chronic alveolar emphysema in horses; bronchial asthma, atony of forestomach and retained placenta in large and small ruminants; gangrenous mastitis in sheep; oedema disease in piglets; cases of insect and snake bites; transport disease; for anaesthesia of the nasal mucosa.

CONTRAINDICATIONS

Not established.

MODE OF ADMINISTRATION (Rp)

Intramuscularly, subcutaneously, externally.

TARGET SPECIES

Ruminants, pigs, dogs.

DOSAGE

SPECIES	Allergovet 10% solution for injection, ml
Large ruminants	3.0 – 6.0
Horses	1.0 – 5.0
Small ruminants	0.5 – 0.8
Pigs	0.5 – 0.7
Dogs	0.1 – 0.4

SPECIES

Note: In shock conditions the dosage levels may be doubled. Topically: for anaesthesia of the mucosa use the 10% solution on drops. Parenterally: average doses - 1 - 2 mg/ kg b.w.

SIDE EFFECTS

Depression, mouth dryness, hyposthenuria (reduced urine output).

WITHDRAWAL PERIOD

For meat - 1 day after the last administration of the preparation.

For milk - 1 day after the last administration of the preparation.

STORAGE

In the original packing, well closed, in dry and well-ventilated facilities, protected from direct sunlight at temperature between 15° and 25°C.

SHELF LIFE

Three (3) years from the date of manufacture.

PACKAGING

Multidose vials of 25 and 50 ml.