JIVET® 2%, 4%, 8% PREMIX

PHARMASTIM® 2%, 4%, 8% PREMIX

(flavophospholipol)

COMPOSITION

	Jivet/Pharmastim 2% premix	Jivet/ Pharmastim 4% premix	Jivet/ Pharmastim 8% premix
Flavophospholipol	2 g	4 g	8 g
Excipients	up to 100 g	up to 100 g	up to 100 g

PHARMACOLOGICAL ACTION

Flavophospholipol is a glycolipid growth promoter (nutritive antibiotic) which induces an effect mainly against Gram-positive microorganisms. It is not absorbed by the gastrointestinal tract and does not accumulate in the tissues of treated animals. Flavophospholipol stimulates growth rate and productivity of the animals, improves feed conversion efficiency (decreases feed intake for 1 kg b.w.). Its effect is contributed to transformations in the composition of the microflora as a result of which prevalence is given to positive microorganisms (synthesizing vitamins, amino acids, enzymes, etc.). In ruminants it enhances the synthesis of volatile fatty acids, propionic acid in particular, in the forestomachs; decreases the formation of ammonia and methane, and accelerates cellulose decomposition. It does not create cross-resistance to other antibiotics and to sulphonamides. Flavophospholipol recovers the sensitivity of resistant bacteria (with R-plasmid extrachromosomal resistance) of Enterobacteriaceae family (E. coli, Salmonella spp., etc.) that have acquired transferable resistance to therapeutic antibiotics and sulphonamides. It is compatible with common feed additives as well as with medicinal products applied in feed.

INDICATIONS

For promoting growth and improving feed efficiency in chickens, pigs, and calves during the growing and fattening period.

For restoring the sensitivity of the resistant bacteria from the family Enterobacteriaceae ( E. coli, Salmonella spp., etc.) towards hemotherapeutics (antibiotics, sulphonamides) and for restricting their dispersion in the environment.

CONTRAINDICATIONS

Not established.

Do not apply in waters with fish population.

MODE OF ADMINISTRATION

Orally, well homogenized into feed.

In order to reach uniform homogenization with feed, it is recommended to mix the measured quantity of the preparation (calculated on the basis of the prescribed dose) on stages in the following order: up to 10 kg feed; up to 100 kg feed; and up to 1000 kg feed.

TARGET SPECIES

Chickens, pigs, and calves.

DOSAGE

SPECIES	Flavophospholipol ppm	Jivet/Pharmastim 2% premix g/ ton feed	Jivet/Pharmastim 4% premix g/ ton feed	Jivet/Pharmastim 8% premix g/ ton feed
Chickens for fattening	4 – 8	200 – 400	100 – 200	50 – 100
Pigs	5 – 20	250 – 1000	125 – 500	62.5 – 250
Calves for fattening	6 – 16	300 – 800	150 – 400	75 – 200

SIDE EFFECTS

Not established.

WITHDRAWAL PERIOD

Zero (0) days.

STORAGE

In the original packing, well closed, in dry and well-ventilated facilities, protected from direct sunlight at temperature between 15° and 25°C.

SHELF LIFE

Two (2) years from the date of manufacture.

PACKAGING

25 kg PE-lined multi-layer paper bags.