YUMAMYCIN® 1%, 5% PREMIX

(maduramicin ammonium)

COMPOSITION

	Yumamycin 1% premix	Yumamycin 5% premix
Maduramicin ammonium	1 g	5 g
Excipients	up to 100 g	up to 100 g

PHARMACOLOGICAL ACTION

Maduramicin is a monovalent glycoside polyether ionophore antibiotic. It induces an anticoccidial effect on the asexual forms (sporozoites, merozoites and falciform bodies) of the endogenous development of coccidia (Eimeria tenella, E. acervulina, E. mivati, E. brunetti, E. maxima, E. necatrix) in poultry, some resistant forms to other ionophore antibiotics included. Its anticoccidial activity is due to disorder in ion metabolism (potassium and sodium in particular). It is incompatible with tiamulin.

INDICATIONS

For prevention and control of coccidiosis in chickens for fattening, pullets reared for laying up to 16 weeks of age; turkey poults up to 12 weeks of age.

CONTRAINDICATIONS

Do not treat animals with feed supplemented with Yumamycin while receiving, or for at least seven days before or after receiving feed containing tiamulin. Do not mix with another anticoccidial. Do not administer to horses or other equines.

MODE OF ADMINISTRATION

Orally, thoroughly mixed into feed.

In order to reach uniform homogenization with feed, it is recommended to mix the measured quantity of the preparation (calculated on the basis of the prescribed dose) on stages in the following order: up to 10 kg feed; up to 100 kg feed; and up to 1000 kg feed.

TARGET SPECIES

Poultry.

DOSAGE

SPECIES	Maduramicin ammonium ppm	Yumamycin 1% premix g/ ton feed	Yumamycin 5% premix g/ ton feed
Chickens for fattening	5	500	100
Replacement layers up to 16 weeks of age	5	500	100
Turkey poults up to 1 2 weeks of age	5	500	100

SIDE EFFECTS

In case of overdose, possible suppression of growth and intoxication (with clinical manifestation such as loss of appetite, tremor, paresis of limbs and death) could occur.

WITHDRAWAL PERIOD

For meat - 5 (five) days after the last administration of the product.

STORAGE

In the original packing, well closed, in dry and well-ventilated facilities, protected from direct sunlight at temperature between 15° and 25°C.

SHELF LIFE

Two (2) years from the date of manufacture.

PACKAGING

25 kg PE-lined multi-layer paper bags.

WARNING

Do not leave or dispose of medicated feed or premix containing maduramicin in places accessible to other domestic or wild animal species.