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APIs / APIs for veterinary use / Tiamulin Base 75% oily concentrate

TIAMULIN BASE 75% oily concentrate

structure

Molecular formula:

C28H47NO4S

Molecular weigh:

493,8

CAS registry No:

55297-95-5

Presentation:

Oil solution or suspension

Category:

Pleuromutilins; Antibacterial

Application:

For veterinary use only.
For production of pharmaceutical products.

Quality:

Company requirements

Contents:

Not less than 71.25% and not more than 78.75%

Most commonly used drug forms:

solution for injections

Packing:

20 kg in stainless steel container, placed in a fiber drum.

Re-test period:

1 year from manufacturing date.

Storage:

In a dry place, protected from light, at a temperature below 25°C.

Pharmacological action:

Tiamulin is semi-synthetic derivative of Pleuromutilin, which belongs to the class of diterpenes and it possesses a quite rigid tricyclic structure. Tiamulin is extremely active against gram-positive organisms such as streptococci, staphylococci and against mycoplasmas and Brachyspira.

Members of other 16 anaerobic species including Bacteroides fragilis and Clostridium perfringens with no exception are sensitive to Tiamulin. The most interesting biological activity of Tiamulin however, is its significant effectiveness against mycoplasmas of considerable veterinary importance, causing infections of the respiratory and urogenital tracts, mammary glands, joints or eyes of various poultry and livestock species, surpasses antibiotics which are considered the treatment of choice of these types of infections as Tetracycline hydrochloride and Tylosin tartrate.

In veterinary medicine Tiamulin is used for treatment, control and prevention of swine dysentery, swine pneumonia and mycoplasmal diseases in pigs and poultry.